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Madrigal Pharmaceuticals Signs Global siRNA Licensing Deal With Ribo
Madrigal Pharmaceuticals Inc. has announced a global licensing agreement with Suzhou Ribo Life Science Co. Ltd. to develop six preclinical small interfering RNA programs targeting metabolic dysfunction-associated steatohepatitis (MASH). The deal includes an upfront payment of $60 million to Ribo, with potential milestone payments up to $4.4 billion plus royalties. This agreement expands Madrigal’s pipeline beyond its approved MASH therapy, Rezdiffra, aiming to provide genetically targeted treatment approaches for the liver disease.